Hello!
Alex from Koinly here 
Usually cost-basis issues are related to missing transactions or some other import issue so even if you were able to manually edit the cost-basis it would likely not fix the situation entirely and might even cause you to under-report your profits which could have some bad implications.
If USD to USDC transaction is showing a profit then there must be an issue with the transaction history.
With that said, it’s possible to manually edit the cost-basis by finding the transaction where you acquired the asset you want to change, and edit the “worth” of it. That way it will have a different cost-basis when you go to dispose it.
But note that your cost-basis method will determine a lot in this case.
There can be cases where Koinly fails to import something and you end up having to manually add some transactions. This is not the experience we want to provide, we want everything to be as automated as possible, so if that’s the case then it’s more than likely that we are working on a solution for it. 
I’m sorry for the inconvenience this causes meanwhile, but rest assured that we are doing our best to make the tax calculation process as easy as possible!
If you need help with getting the cost-basis showing properly then please send us an email at [email protected] so we can give you more direct support 
Best regards,
Alex